The Challenge of Benzodiazepines Part 2

Updated: Oct 25th, 2025

Published: OCt 25th, 2025

Presentation Synopsis

This educational presentation by the Opioid Remediation Collaborative (ORCNM) builds on foundational knowledge of benzodiazepines by focusing on withdrawal, clinical management, and prevention strategies. It is designed to help providers understand the complexities of benzodiazepine dependence and safely manage patients through tapering and recovery.

The presentation covers withdrawal syndromes, risk factors, and both outpatient and inpatient management approaches. It also emphasizes monitoring strategies, prevention best practices, and the importance of patient-centered care when addressing long-term benzodiazepine use.

Learning Objectives

  • Understand the difference between physical dependence and benzodiazepine use disorder

  • Recognize the clinical syndromes associated with benzodiazepine withdrawal, including rebound, recurrence, and severe withdrawal symptoms

  • Identify risk factors for complicated withdrawal, including high-dose use, co-occurring substance use, and underlying medical conditions

  • Understand best practices for benzodiazepine tapering, including gradual dose reduction and patient-specific considerations

  • Describe outpatient and inpatient management strategies for benzodiazepine withdrawal

  • Identify adjunctive treatments and supportive therapies used during withdrawal management

  • Recognize the symptoms and duration of post-acute withdrawal syndromes

  • Understand appropriate monitoring strategies, including urine drug screening and ongoing clinical assessment

  • Identify prevention strategies and prescribing considerations to reduce long-term benzodiazepine-related harm

  • Emphasize the importance of a patient-centered, cautious, and evidence-informed approach to benzodiazepine discontinuation

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